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Cocaine Fact Sheet
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What is cocaine?
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Cocaine is a highly addictive stimulant drug that is derived from the leaves of a coca plant that is native to South America1
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In 2020 alone, 5.2 million people 12+ in the U.S. reported cocaine use within the last year1
Intended use
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Cocaine may be used as a topical local anesthetic for the upper respiratory tract or to reduce bleeding in mucous membranes3
Common names
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Blow, Coca, Coke, Crack, Flake, Snow, and Soda Cot3
Forms
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Snorting grinded powder up the nose (lasts 15-30 minutes)1
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Rubbing grinded powder on the gums (lasts 10-30 minutes)1
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Dissolving powder and injecting into the bloodstream (lasts 20-60 minutes)1,5
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Smoking cocaine that has gone through a process that crystallizes it into a solid rock called crack (lasts 5-10 minutes)1
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Cocaine is often taken in copious amounts or binges to maintain the level of high1
How cocaine works
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Cocaine raises the level of dopamine in the brain and then prevents the recycling of dopamine, resulting in a buildup between nerve cells1
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This build-up of dopamine interrupts signaling between nerve cells and creates a sensation of euphoria2
Short term health effects
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Dilated pupils, extreme elation/energy, feeling alert, loss of appetite, insomnia, irritability, paranoia, and sensory hypersensitivity1,3
Long term health effects
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Depends on amount consumed and method of use1
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If applied to gums: Bowel decay from reduced blood flow1
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If applied through needle injection: increased risk of developing diseases through needle sharing such as HIV and Hepatitis C1
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If applied through nose: Problems with swallowing, nasal lining decay, nosebleeds, loss of smell and constant runny noses1
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If applied through smoking: respiratory distress, cough, increased chance of lung infection and asthma1
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Serious adverse effects include irregular heartbeat, ischemic heart conditions, sudden cardiac arrest, convulsions, stroke, and death3
Withdrawal
Symptoms
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Depression
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Fatigue
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Increased appetite
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Slowed thinking
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Insomnia1
Given the symptoms of withdrawal, a person may need medical supervision to ensure their safety during the process.6
Overdose
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An overdose can be intentional or unintentional and is when a large enough amount of cocaine is consumed to have serious adverse health effects, life threatening symptoms or even death1
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Symptoms include difficulty breathing, high blood pressure, high body temperature, hallucinations, and extreme agitation or anxiety1
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Overdose is more likely when Cocaine is used in combination with other drugs such as Heroin, alcohol and many more1
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Cocaine is often cut with other substances to maximize its volume. These added substances can increase the likelihood of an overdose1.
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These substances often include laxatives, caffeine, laundry detergent, cornstarch, baking soda, creatine or fentanyl1
Addiction treatment
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Therapeutic interventions: Cognitive Behavioral Therapy (CBT), Contingency Management, Community-based Recovery Groups, Therapeutic Communities1
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Currently there are no medications specifically designed for the treatment of cocaine addiction, but such medications are in development1
References
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Cocaine Research Report
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Cocaine
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Cocaine: Drug Fact Sheet
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Compound Summary: Cocaine
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Substance Use – Cocaine
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Withdrawal